Ulipristal acetate: understanding its uses for EC and beyond
Downloadable resources
New Uses for Ulipristal Acetate: Background and Key Takeaways
A recent study that includes ulipristal acetate (UPA) as part of an abortion regimen may put a spotlight on EC pills, since UPA is currently marketed and indicated for EC use. The European Consortium for Emergency Contraception (ECEC) and the American Society for Emergency Contraception (ASEC) created this resource to provide background information about emergency contraceptive (EC) pills and medication abortion regimens. Publication of the new study creates renewed opportunities to educate about the importance of EC and its role in preventing pregnancy; dispel myths around EC pill use, safety, and mechanism of action; and uplift the importance of both EC and medication abortion while clarifying the differences.
New Uses for Ulipristal Acetate: Summary
This document summarizes key takeaways about new potential uses for ulipristal acetate (UPA), as a forthcoming study investigated use of UPA and misoprostol for early pregnancy termination.
New Data on Ulipristal Acetate and Misoprostol for Medication Abortion — A Step Forward?
By Daniel Grossman, MD ​
In the current issue of NEJM Evidence, Winikoff et al. report on an early phase study in humans of ulipristal acetate used for medication abortion.1 The researchers found that ulipristal acetate 60 mg used together with a single dose of misoprostol 800 μg was 97.0% (95% confidence interval, 94.1 to 99.9%) effective to induce a complete abortion up to 63 days of pregnancy. Although the study is small and lacks a concurrent comparison group, the findings suggest that this regimen may be effective for medication abortion, and more research is warranted.
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To learn more about EC:
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To learn more about abortion:
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I Need An A: https://www.ineedana.com/
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Plan C: https://www.plancpills.org/
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Aid Access: https://aidaccess.org/en/
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Abortionfinder: https://www.abortionfinder.org/​
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Versions of these documents adapted to a global context are available here
